Apoptosis mapping in space and time of 3D tumor ecosystems reveals transmissibility of cytotoxic cancer death. PLOS Computational Biology, 17(3), e1008870.
Our publications
Since its creation, Institut Roche has translated its expertise into numerous successful scientific publications
The Caspase-1/IL-18 Axis of the Inflammasome in Tumor Cells: A Modulator of the Th1/Tc1 Response of Tumor-Infiltrating T Lymphocytes in Colorectal Cancer. Cancers, 13(2), 189.
Mutala, L. B., Deleine, C., Karakachoff, M., Dansette, D., Ducoin, K., Oger, R., Rousseau, O., Podevin, J., Duchalais, E., Fourquier, P., Thomas, W., Gourraud, P. A., Bennouna, J., Brochier, C., Gervois, N., Bossard, C., & Jarry, A. (2021).
https://doi.org/10.3390/cancers13020189Natural history of Type 2 and 3 spinal muscular atrophy: 2-year NatHis-SMA study. Annals of clinical and translational neurology, 8(2), 359–373.
Annoussamy, M., Seferian, A. M., Daron, A., Péréon, Y., Cances, C., Vuillerot, C., De Waele, L., Laugel, V., Schara, U., Gidaro, T., Lilien, C., Hogrel, J. Y., Carlier, P., Fournier, E., Lowes, L., Gorni, K., Ly-Le Moal, M., Hellbach, N., Seabrook, T., Czech, C., … NatHis-SMA study group (2021).
https://doi.org/10.1002/acn3.51281DNA repair-based classification of melanoma cell lines reveals an effect of mutations in BRAF and NRAS driver genes on DNA repair capacity. Biorxiv.
Sauvaigo, S., Benkhiat, M., Braisaz, F., Girard, J., Libert, S., Mouret, S., de Fraipont, F., Aspord, C., Bouquet, F., & Leccia, M. T. (2020).
https://doi.org/10.1101/2020.04.29.067900Longitudinal analysis of organ-specific tumor lesion sizes in metastatic colorectal cancer patients receiving first line standard chemotherapy in combination with anti-angiogenic treatment. Journal of pharmacokinetics and pharmacodynamics, 47(6), 613–625.
Mercier, F., Kerioui, M., Desmée, S., Guedj, J., Krieter, O., & Bruno, R. (2020).
https://doi.org/10.1007/s10928-020-09714-zBayesian inference using Hamiltonian Monte-Carlo algorithm for nonlinear joint modeling in the context of cancer immunotherapy. Statistics in medicine, 39(30), 4853–4868.
Kerioui, M., Mercier, F., Bertrand, J., Tardivon, C., Bruno, R., Guedj, J., & Desmée, S. (2020).
https://doi.org/10.1002/sim.8756“Reading the Mind in the Eyes” in Autistic Adults is Modulated by Valence and Difficulty : An InFoR Study. Autism Research, 14(2), 380-388.
Baltazar, M., Geoffray, M., Chatham, C., Bouvard, M., Martinez Teruel, A., Monnet, D., Scheid, I., Murzi, E., Couffin-Cadiergues, S., Umbricht, D., Murtagh, L., Delorme, R., Ly Le-Moal, M., Leboyer, M., & Amestoy, A. (2020).
https://doi.org/10.1002/aur.2390Low expression of ANT1 confers oncogenic properties to rhabdomyosarcoma tumor cells by modulating metabolism and death pathways. Cell Death Discovery, 6(1).
Vial, J., Huchedé, P., Fagault, S., Basset, F., Rossi, M., Geoffray, J., Soldati, H., Bisaccia, J., Elsensohn, M. H., Creveaux, M., Neves, D., Blay, J. Y., Fauvelle, F., Bouquet, F., Streichenberger, N., Corradini, N., Bergeron, C., Maucort-Boulch, D., Castets, P.,. . . Castets, M. (2020).
https://doi.org/10.1038/s41420-020-00302-1IDO Targeting in Sarcoma : Biological and Clinical Implications. Frontiers in Immunology, 11.